Hydroxyurea effects

Over the next two months, the HU did reduce my platelet count from a high of 719 to 440. Unfortunately, it also affected my RBC and Hb, requiring another 2 unit transfusion on August 18th. Dr then prescribed Procrit (20,000 units once per week) to counter the HU and stimulate RBC generation. By Sept 7th, my Hb had dropped to a new low of 7.0. I got another 2 units of blood and was switched from the HU to Anagrelide (.5 mg twice a day).